What biochemical reaction is catalyzed by -secretase? Why was it proposed that a chemical inhibitor of this

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What biochemical reaction is catalyzed by γ-secretase? Why was it proposed that a chemical inhibitor of this activity might be a useful drug for treating Alzheimer's disease? What possible side effects of such a drug would complicate this use?

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Molecular Cell Biology

ISBN: 978-1429234139

7th edition

Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott

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Question Posted: Apr 17, 2018 07:25 AM

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What biochemical reaction is catalyzed by -secretase? Why was it proposed that a chemical inhibitor of this

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secretase is an intramembrane protease When it was found that gsecretase cleaves the intramem...View the full answer

Molecular Cell Biology

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