8. You start a 19-year-old man on phenytoin in a dose of 300 mg/day to control...

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8. You start a 19-year-old man on phenytoin in a dose of 300 mg/day to control generalized (grand mal) seizures. Ten days later, he is brought to an emer- gency room following a seizure. His phenytoin level is found to be 5 ug/mL and the phenytoin dose is increased to 600 mg/day. Two weeks later, he returns to your office complaining of drowsiness and ataxia. At that time his phenytoin level is 30 ug/mL. Assuming patient compliance with previous therapy, which of the following dose regimens should provide a phenytoin plasma level of 15 ug/mL (therapeutic range: A. 350 mg/day B. 400 mg/day C. 450 mg/day D. 500 mg/day E. 550 mg/day 10-20 ug/mL)? 8. You start a 19-year-old man on phenytoin in a dose of 300 mg/day to control generalized (grand mal) seizures. Ten days later, he is brought to an emer- gency room following a seizure. His phenytoin level is found to be 5 ug/mL and the phenytoin dose is increased to 600 mg/day. Two weeks later, he returns to your office complaining of drowsiness and ataxia. At that time his phenytoin level is 30 ug/mL. Assuming patient compliance with previous therapy, which of the following dose regimens should provide a phenytoin plasma level of 15 ug/mL (therapeutic range: A. 350 mg/day B. 400 mg/day C. 450 mg/day D. 500 mg/day E. 550 mg/day 10-20 ug/mL)?