Answered step by step
Verified Expert Solution
Link Copied!

Question

1 Approved Answer

Which of the following statements BEST describes the mechanism of action of penicillin? Penicillin acts as a mimetic of the D-Ala-D-Ala moiety of the

 

Which of the following statements BEST describes the mechanism of action of penicillin? Penicillin acts as a mimetic of the D-Ala-D-Ala moiety of the normal substrate, and binds the active site of the transpeptidase enzyme leading to irreversible inhibition of the enzyme and inhibition of cell wall synthesis. The binding of the B-lactam ring of penicillin to a transpeptidase enzyme stabilises the enzyme and leads to increased cross-linking between glycine residues. The binding of the B-lactam ring of penicillin to the transpeptidase enzyme, stimulates cross linking activity and results in a cell wall that is impermeable to antibiotics. Penicillin inhibits the transpeptidation enzymes that stabilise ribosomal structure and thus, interferes directly with protein synthesis.

Step by Step Solution

3.32 Rating (164 Votes )

There are 3 Steps involved in it

Step: 1

Option C Penicillin kills bacteria through binding of the betalactam ring to DDtranspeptidase ... blur-text-image

Get Instant Access to Expert-Tailored Solutions

See step-by-step solutions with expert insights and AI powered tools for academic success

Step: 2

blur-text-image

Step: 3

blur-text-image

Ace Your Homework with AI

Get the answers you need in no time with our AI-driven, step-by-step assistance

Get Started

Recommended Textbook for

Microbiology A Systems Approach

Authors: Marjorie Kelly Cowan

4th edition

978-007340243, 73402435, 978-0073402437

More Books

Students also viewed these Biology questions

Question

What do I have experience doing?

Answered: 1 week ago