Prepare total solubility curves for the following species across a broad pH range

(a) Caproic acid (C₈H₁₆O₂) is a colorless, oily, naturally occurring fatty acid in animal fats and oils. Its water solubility is 9.67 g/kg 25^οC with a value of pK_a = 4.85.

(b) The least-soluble amino acid is tyrosine (Tyr, Y, C₉H_1 1NO₃), which occurs in proteins and is involved in signal transduction as well as photosynthesis, where it donates an electron to reduce oxidized chlorophyll. Its water solubility is 0.46 g/kg at 25^οC, at which its pK^c _a = 2:24 and its pK^a_a = 9:04 (neglect deprotonation of phenolic OH-group, pK_a = 10.10).

Calculate the solubility of each component in the following bodily fluids:
Arterial blood plasma pH = 7.4

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(~pH 1 to pH 11).