Suggest probable consequences of the following real or possible hemoglobin mutations a At 146 (HC3) His Asp b At 92 (F8) His Leu In each case, tell whether a single nucleotide change is sufficient for the mutation ...

a b Because F8 is involved in heme binding the heme should be unstable L ...

Suggest probable consequences of the following real or possible hemoglobin mutations. a. At 146 (HC3) His

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Suggest probable consequences of the following real or possible hemoglobin mutations.
a. At β146 (HC3) His → Asp
b. At β92 (F8) His → Leu
In each case, tell whether a single-nucleotide change is sufficient for the mutation.

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Biochemistry Concepts and Connections

ISBN: 978-0321839923

1st edition

Authors: Dean R. Appling, Spencer J. Anthony Cahill, Christopher K. Mathews

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Question Posted: Apr 21, 2016 04:14 AM

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Suggest probable consequences of the following real or possible hemoglobin mutations. a. At 146 (HC3) His

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a b Because F8 is involved in heme binding the heme should be unstable L...View the full answer

Biochemistry Concepts and Connections

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