Tranexamic acid, a drug useful against blood clotting, Is prepared commercially from p-methyl Benzonitrile. Formulate the steps
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Tranexamic acid, a drug useful against blood clotting, Is prepared commercially from p-methyl Benzonitrile. Formulate the steps likely to be used in the synthesis. (Don?t worry about cis-trans isomers; heating to 300 ?C interconvert?s the isomers.)
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H. CO2H Tranexamic acid H2NCH2
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OH NBS excess P PhCO22 NH3 CHBr CN CH3 H3O OH CH3 OH HOC H H RhC CHNH H CH2NH2 ...View the full answer
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