Upon activation by a receptor, a G protein exchanges bound GDP for GTP, rather than phosphorylating GDP that is already bound Similarly, the subunit GTP complex has a slow GTPase activity that hydrolyzes bound GTP, rather than exchanging it for GDP Describe experimental evidence that would be consi...

One could treat a G proteinGDP complex with 32P ATP and ask whether radiol ...

Upon activation by a receptor, a G protein exchanges bound GDP for GTP, rather than phosphorylating GDP

Question:

Upon activation by a receptor, a G protein exchanges bound GDP for GTP, rather than phosphorylating GDP that is already bound. Similarly, the α subunit-GTP complex has a slow GTPase activity that hydrolyzes bound GTP, rather than exchanging it for GDP. Describe experimental evidence that would be consistent with these conclusions.