What is the difference between pure and mixed noncompetitive inhibition?
Answer to relevant QuestionsWhy can we say that having a pure non- competitive inhibitor present is similar to just having less enzyme present? For the following aspartase reaction (see Question 28) in the presence of the inhibitor hydroxymethylaspartate, determine KM and whether the inhibition is competitive or noncompetitive. What are some possible advantages to the cell in combining phosphorylation with allosteric control? Explain why the second phase of the chymotrypsin mechanism is slower than the first phase. What is a homotropic effect? What is a heterotropic effect?
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