Grignard reagents react with oxetane, a four-membered cyclic ether, to yield primary alcohols, but the reaction is
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Grignard reagents react with oxetane, a four-membered cyclic ether, to yield primary alcohols, but the reaction is much slower than the corresponding reaction with ethylene oxide. Suggest a reason for the difference in reactivity between oxetane and ethyleneoxide.
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1. RM9X 2. H30* RCH2CH2CH2OH Oxetane
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The mechanism of Grignard addition to oxetane is the same as the mec...View the full answer
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