Refer to the journal eCAM (November 2006) assessment of the quality of the methodology used in studies of the treatment for Alzheimer€™s disease, presented in Exercise. Data on the quality of the methodology (using the Wong scale) for each in a sample of 13 studies are reproduced in the next table and saved in the TREATAD file. According to the researchers, a study with a Wong score below 18 used a methodology that €œfails to support the author€™s conclusions€ about the treatment of Alzheimer€™s. Use Wilson€™s adjustment to estimate the proportion of all studies on the treatment of Alzheimer€™s disease with a Wong score below 18. Construct a 99% confidence interval around the estimate and interpret the result.

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22 21 18 19 20 15 19 20 15 20 17 20 21