If some cell-surface receptors, including Notch, can rapidly signal to the nucleus by activating latent transcription regulators

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If some cell-surface receptors, including Notch, can rapidly signal to the nucleus by activating latent transcription regulators at the plasma membrane, why do most cell surface receptors use long, indirect signaling cascades to influence gene transcription in the nucleus?

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Essential Cell Biology

ISBN: 9780393680362

5th Edition

Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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