The locomotion of fibroblasts in culture is immediately halted by the drug cytochalasin, whereas colchicine causes fibroblasts
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The locomotion of fibroblasts in culture is immediately halted by the drug cytochalasin, whereas colchicine causes fibroblasts to cease to move directionally and to begin extending lamellipodia in seemingly random directions. Injection of fibroblasts with antibodies to the intermediate filament protein vimentin has no discernible effect on their migration. What do these observations suggest to you about the involvement of the three different cytoskeletal filaments in fibroblast locomotion?
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Based on the provided observations we can infer the following regarding the involvement of cytoskele...View the full answer
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Related Book For 
Essential Cell Biology
ISBN: 9780393680362
5th Edition
Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter
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