Which of the following mutational changes would you predict to be the most deleterious to gene function?

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Which of the following mutational changes would you predict to be the most deleterious to gene function? Explain your answers.

1. Insertion of a single nucleotide near the end of the coding sequence.

2. Removal of a single nucleotide near the beginning of the coding sequence.

3. Deletion of three consecutive nucleotides in the middle of the coding sequence.

4. Substitution of one nucleotide for another in the middle of the coding sequence.

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Molecular Biology Of The Cell

ISBN: 9780815344322

6th Edition

Authors: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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Question Posted: Jun 18, 2020 03:21 AM

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Which of the following mutational changes would you predict to be the most deleterious to gene function?

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The mutations given will have the following effects on the proteinamino acid sequence Insertion of a ...View the full answer

Molecular Biology Of The Cell

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