Why is localization of Ran-GAP in the nucleus and Ran-GEF in the cytoplasm necessary for unidirectional transport
Question:
Why is localization of Ran-GAP in the nucleus and Ran-GEF in the cytoplasm necessary for unidirectional transport of cargo proteins containing an NES?
Fantastic news! We've Found the answer you've been seeking!
Step by Step Answer:
Answer rating: 66% (6 reviews)
Ranguanine nucleotideexchange factor RanGEF must be present in the nu...View the full answer
Answered By
Joseph Mwaura
I have been teaching college students in various subjects for 9 years now. Besides, I have been tutoring online with several tutoring companies from 2010 to date. The 9 years of experience as a tutor has enabled me to develop multiple tutoring skills and see thousands of students excel in their education and in life after school which gives me much pleasure. I have assisted students in essay writing and in doing academic research and this has helped me be well versed with the various writing styles such as APA, MLA, Chicago/ Turabian, Harvard. I am always ready to handle work at any hour and in any way as students specify. In my tutoring journey, excellence has always been my guiding standard.
4.00+
1+ Reviews
10+ Question Solved
Related Book For
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
Question Posted:
Students also viewed these Life Sciences questions
-
Movement of glucose from one side to the other side of the intestinal epithelium is a major example of transcellular transport. How does the Na + /K + ATPase power the process? Why are tight...
-
Consider a nucleus that undergoes decay. (a) Is the radius of the resulting daughter nucleus greater than, less than, or equal to the radius of the original nucleus? (b) Choose the best explanation...
-
Why was the need for an RNA intermediary in protein synthesis most obvious in eukaryotes? How did researchers first demonstrate that RNA synthesis occurred in the nucleus and that protein synthesis...
-
The jet plane starts from rest at s = 0 and is subjected to the acceleration shown. Determine the speed of the plane when it has traveled 1000 ft. Also, how much time is required for it to travel...
-
Arnold learned something very valuable as a teenager from his dad. He was told to invest $1,250 at 8% interest at age 20 and leave it alone until age 65. Arnold's dad knew that one strategy that...
-
Briefly describe the standard of care to protect others from harm for each of the following liability situations: a. Property owners b. An attractive nuisance c. Owners and operators of automobiles...
-
A pump moves water horizontally at a rate of \(0.02 \mathrm{~m}^{3} / \mathrm{s}\). Upstream of the pump where the pipe diameter is \(90 \mathrm{~mm}\), the pressure is \(120 \mathrm{kPa}\)....
-
Cray-Z Consultants provides management accounting advice to not-for-profit-firms. It employs three levels of consultants, based on experience and education: partner, senior, and associate. When...
-
Projected financial results for the university's cafeteria for next year are shown. Answer each of the following independent questions. Sales (a) How much is the contribution margin and the...
-
Figure 3-13 shows the development of entity clusters for the Pine Valley Furniture E-R diagram. In Figure 3-13b, explain the following: a. Why is the minimum cardinality next to the DOES BUSINESS IN...
-
The nuclear import of proteins larger than 40 kDa requires the presence of what amino acid sequence? Describe the mechanism of nuclear import. How are nuclear transport receptors able to get through...
-
Imagine that you are evaluating the early steps in translocation and processing of the secretory protein prolactin. By using an experimental approach similar to that shown in Figure 13-7, you can use...
-
Find the general solution of the given differential equation. Give the largest interval I over which the general solution is defined. Determine whether there are any transient terms in the general...
-
Hosts A and B are each connected to a switch S via 10-Mbps links as in Figure 1.21. The propagation delay on each link is 20 s. S is a store-and-forward device; it begins retransmitting a received...
-
Problems 45-50 show scatter diagrams along with a best-fitting line. Match the best-fitting line in each with an appropriate equation named \(\mathrm{A}-\mathrm{H}\). A. \(y=0.5 x-4\) B. \(y=-0.5...
-
Discuss the correlation shown by the following chart. Age-adjusted deaths per 100,000 population 30 25 20 15 10 0 5 Philippines. 0 Thailand 20 South Africa Venezuela Chile Panama Colombia Japan 40...
-
Carry out the following experiment: \(A\) cat has two bowls of food; one bowl contains Whiskas and the other contains some other brand. The cat eats Whiskas and leaves the other untouched. Make a...
-
The following data are the number of years of full-time education \((x)\) and the annual salary in thousands of dollars (y) for 15 persons. Is there a correlation between education and salary, and if...
-
Find the exact value of expression. tan 19/12
-
The May 2014 revenue and cost information for Houston Outfitters, Inc. follow: Sales Revenue (at standard).............. $ 540,000 Cost of Goods Sold (at standard) ..........341,000 Direct Materials...
-
After treating cells with a chemical mutagen, you isolate two mutants. One carries alanine and the other carries methionine at a site in the protein that normally contains valine (Figure Q64). After...
-
Which of the following mutational changes would you predict to be the most deleterious to gene function? Explain your answers. 1. Insertion of a single nucleotide near the end of the coding sequence....
-
Prokaryotes and eukaryotes both protect against the dangers of translating broken mRNAs. What dangers do partial mRNAs pose for the cell?
-
Prob. 1(a). Consider a stock currently trading at $40.25. For a strike price of $38, you want to price both a call and put option that matures 90 days from now. The volatility of the stock (2) is...
-
Wildhorse sells a snowboard, WhiteOut, that is popular with snowboard enthusiasts. Presented below is information relating to Wildhorse's purchases of WhiteOut snowboards during September. During the...
-
The following unadjusted trial balance is prepared at fiscal year-end for Nelson Company. Nelson Company uses a perpetual inventory system. It categorizes the following accounts as selling expenses:...
Study smarter with the SolutionInn App