When an ?-hydroxy amide is treated with Br2 in aqueous NaOH under Hofmann rearrangement conditions, loss of
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When an ?-hydroxy amide is treated with Br2 in aqueous NaOH under Hofmann rearrangement conditions, loss of CO2 occurs and a chain-shortened aldehyde is formed. Propose a mechanism.
Transcribed Image Text:
Он NH2 н NH3 Br2 NaOH, H20 CO2 +
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NH H 32533 H NH Br NaOH HO NH3 NH3 Hofm...View the full answer
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