The following compound has one aldehyde group and two OH groups: Under acidic conditions, either one of

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The following compound has one aldehyde group and two OH groups: Under acidic conditions, either one of the OH groups can function as a nucleophile and attack the carbonyl group, giving rise to two possible ring sizes.

(a) Ignoring stereochemistry (for now), draw both possible rings.

(b) In Section 4.9, we discussed the ring strain associated with different size rings. Based on those concepts, predict which cyclic hemiacetal will be favored in this case.

H. Но Он

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Organic Chemistry

ISBN: 978-0470917800

1st edition

Authors: David R. Klein

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