Question: A Randomized Clinical Trial (RCT) was designed to compare two chemotherapy regimens (Standard vs. Experimental) for patients with advanced pancreatic cancer. A sample size of

A Randomized Clinical Trial (RCT) was designed to compare two chemotherapy regimens (Standard vs. Experimental) for patients with advanced pancreatic cancer. A sample size of 600 per group was chosen to have 80% power to detect a difference of 5 mm in mean tumor size at 6 months, based on an estimated standard deviation of 15 mm. a. Which of the following is an accurate interpretation of the 80% power of this study? (Circle one) We will have an 80% chance of finding a significant difference if the observed mean tumor size differs by 5 mm and the standard deviation is 15 mm. We will have an 80% chance of finding a significant difference if the true mean tumor size of the groups differs by 5 mm and the standard deviation is 15 mm. There is an 80% chance that the observed difference will be 5 mm or more if the standard deviation is 15 mm. At the end of the study, if the standard deviation is 15 mm, then on average 80% of the data will be contained in the confidence interval

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