a. Based on a more conservative answer to Problem 6 (2.7 × 1092 conformations), estimate the conformational entropy change on folding a mole of this protein into a native structure with only one conformation.
b. If the protein folds entirely into a helix with H bonds as the only source of enthalpy of stabilization, and each mole of H bonds contributes - 5 kJ / mol to the enthalpy, estimate ΔH folding . The ends of helices contain fewer hydrogen bonds per residue than in the middle.
(c) From your answers to (a) and (b), estimate ΔG folding for this protein at 25 °C. Is the folded form of the protein stable at 25 °C?