Question: A completely randomized double-blind clinical trial was conducted to compare two drugs, ticrynafen (T) and hydrochlorothiazide (H), for effectiveness in treatment of high blood pressure.

A completely randomized double-blind clinical trial was conducted to compare two drugs, ticrynafen (T) and hydrochlorothiazide (H), for effectiveness in treatment of high blood pressure. Each drug was given at either a low or a high dosage level for 6 weeks. The accompanying table shows the results for the drop (baseline minus final value) in systolic blood pressure (mm Hg).22

Prepare an interaction graph (like Figure 11.7.3).

Ticrynafen (T) Hydrochlorothiazide (H) Low High Low dose dose High dose Mean 139 17.1 No of 5357 patients dose 17.5 58 15.8

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