(a) Isoleucine has been prepared by the following sequence of reactions. Give the structure of compounds A...

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(a) Isoleucine has been prepared by the following sequence of reactions. Give the structure of compounds A through D isolated as intermediates in this synthesis.

(b) An analogous procedure has been used to prepare phenylalanine. What alkyl halide would you choose as the starting material for this synthesis?

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Organic Chemistry

ISBN: 978-0072905014

4th edition

Authors: Francis A. Carey

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Question Posted: Apr 30, 2016 01:59 PM

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(a) Isoleucine has been prepared by the following sequence of reactions. Give the structure of compounds A...

Question:

diethylm Ionut→ALN)→ B (CH204) I. KOH sodium ethoxide 2. HCI Br B Bly C (CHI IBrO4) → D-isoleucine (racemic) NHy H2O heat

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a The first step involves alkylation of diethyl malonate by 2bromobutane In the second s...View the full answer

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