Question: (a) Isoleucine has been prepared by the following sequence of reactions. Give the structure of compounds A through D isolated as intermediates in this synthesis.
(a) Isoleucine has been prepared by the following sequence of reactions. Give the structure of compounds A through D isolated as intermediates in this synthesis.
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(b) An analogous procedure has been used to prepare phenylalanine. What alkyl halide would you choose as the starting material for this synthesis?
diethylm IonutALN) B (CH204) I. KOH sodium ethoxide 2. HCI Br B Bly C (CHI IBrO4) D-isoleucine (racemic) NHy H2O heat
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a The first step involves alkylation of diethyl malonate by 2bromobutane In the second s... View full answer
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