Question: A person with a rare genetic disease has a sample of her chromosomes subjected to in situ hybridization using a probe that is known to

A person with a rare genetic disease has a sample of her chromosomes subjected to in situ hybridization using a probe that is known to recognize band p11 on chromosome 7. Even though her chromosomes look cytologically normal, the probe does not bind to this person's chromosomes. How would you explain these results? How would you use this information to positionally clone the gene that is related to this disease?

Step by Step Solution

★★★★★

3.55 Rating (162 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock

One would conclude that she has a deletion of the gene t... View full answer

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Document Format (1 attachment)

894-M-S-B-G (632).docx

120 KBs Word File

Students Have Also Explored These Related Biology Questions!

The cells from a malignant tumor were subjected to in situ hybridization using a probe that recognizes a unique sequence on chromosome 14. The probe was detected only once in each of these cells....

Two techniques commonly used to study the expression patterns of genes that play a role in development are Northern blotting and in situ hybridization. As described in Chapter 20, Northern blotting...

A person is born with one X chromosome, zero Y chromosomes, trisomy 21, and two copies of the other chromosomes. How many chromosomes does this person have altogether? Explain whether this person is...

Alternative Dispute Resolution The Search for Alternatives to Litigation Legislatures have tried to find alternatives to costly litigation. These alternatives are called \"alternative dispute...

A laboratory test for a rare disease affecting 2% of the population is either positive, indicating the rare disease is present, or negative, indicating the disease is not present. However, when...

Answer these posts and ask a question at the end. Post 1 When looking on Monster for jobs I came across an accounts payable specialist which interested me. You are required to have in-dept accounts...

[Allergy Injuries] Drug company ABC Drugs introduced a new over-the-counter allergy pill guaranteed to prevent sneezing and sniffling for twenty-four hours after the consumption of one pill. The...

You landed a summer internship with a company that processes dental insurance claims for insurance companies. The company receives the insurance claims from dental offices, achieves authorization...

Untitled you landed a summer internship with a company that processes dental insurance claims for insurance companies. The company receives the insurance claims from dental offices, achieves...

you landed a summer internship with a company that processes dental insurance claims for insurance companies. The company receives the insurance claims from dental offices, achieves authorization...

In problem, evaluate dy and Îy for each function for the indicated values. y f(x) = 100(x-4 :x=2,dx = =-0.1

Apple, with its almost 300 company-owned stores, uses independent intermediaries, which it refers to as third-party resellers. For its Mac computers, Apple is very careful about the intermediaries it...

Manufacturing Costs Actual Costs Standard Cost at Actual Volume Budgeted Cost Direct materials $80,300 $76,000 $71,250 Direct labor 77,000 72,500 68,400 Factory overhead 44,800 48,000 45,600 Total...

Which of the following statements about crowding out is true? a. It is caused by a budget surplus. b. It is not caused by a budget defi cit. c. It cannot completely offset the multiplier effect of...

What events does the RecA protein facilitate?

According to the double-strand break model, does gene conversion necessarily involve DNA mismatch repair? Explain.

Briefly describe three ways that antibody diversity is produced.

A builder is offering $123,737 loans for his properties at 9 percent for 25 years. Monthly payments are based on current market rates of 9.5 percent and are to be fully amortized over 25 years. The...

Problem Solution 6-44 Which car has a lower EUAC if the owner can earn A 5% in his best investment. Contributed by Paul R. McCright, University of South Florida Toyota Toyota Corolla Prius $19,200...

The greater use of debt by corporations since the late 1960s is best shown by the a) declining interest coverage ratio. b) small amount of common stock sold. d) inability of earnings to keep up with...