Question: A study was conducted to demonstrate the effectiveness of an investigational drug product in reducing the number of epileptic seizures in patients who have not

A study was conducted to demonstrate the effectiveness of an investigational drug product in reducing the number of epileptic seizures in patients who have not been helped by standard therapy. Thirty patients participated in the study, with 15 randomized to the drug treatment group and 15 to the placebo group. Patient demographic data are displayed here.

A study was conducted to demonstrate the effectiveness of an

a. Do the groups appear to be comparable in terms of these demographic variables?
b. Are the mean ages or durations of illness different? How would you make this­comparison?
c. How might you compare the sex distributions of the two groups?

Group Iavestigational Drug (ni = 15) Placebo (n2 = 15) Age (yr) Gender Duration of illness (yr) Mean (ESD) 10.7 (6.5) Mean (ESD) 372105 39.5 (9.6) Range 19-68 20 10 21-65 16 14 11.5 (7.3) 1-26 Range 1-18

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