Question: A vaccine is claimed to be effective in preventing a rare disease that occurs in about one of every 100,000 people. Explain why a randomized

A vaccine is claimed to be effective in preventing a rare disease that occurs in about one of every 100,000 people. Explain why a randomized clinical trial comparing 100 people who get the vaccine to 100 people who do not get it is unlikely to be worth doing. Explain how you could use a case-control study to investigate the efficacy of the vaccine.

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