As shown in figure 23.5, the Claisen reaction is reversible. That is, a ??keto ester can be

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As shown in figure 23.5, the Claisen reaction is reversible. That is, a ??keto ester can be cleared by base into two fragments. Using curved arrows to indicate electron flow, show the mechanism by which this cleavage occurs.

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Organic Chemistry

ISBN: 9780495112587

7 Edition

Authors: John McMurry

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Question Posted: Mar 04, 2011 05:53 AM

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As shown in figure 23.5, the Claisen reaction is reversible. That is, a ??keto ester can be

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OEt 1 equiv. NaOH Нэс" OEt Ethano!

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off ore OH H3C OEt OEt addition of hydroxide acidbase reaction CO OH OO OEI elimi...View the full answer

Organic Chemistry

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