Question: Carbon monoxide binds to Fe in hemoglobin some 200 times more strongly than oxygen. This is the reason why CO is a toxic substance. The

Carbon monoxide binds to Fe in hemoglobin some 200 times more strongly than oxygen. This is the reason why CO is a toxic substance. The metal-to-ligand sigma bond is formed by donating a lone pair from the donor atom to an empty sp3d2 orbital on Fe.
(a) On the basis of electronegativities, would you expect the C or O atom to form the bond to Fe?
(b) Draw a diagram illustrating the overlap of the orbitals involved in the bonding.

Step by Step Solution

★★★★★

3.24 Rating (168 Votes )

There are 3 Steps involved in it

1 Expert Approved Answer

Step: 1 Unlock

a Since carbon is less electronegative than oxygen it is mor... View full answer

Question Has Been Solved by an Expert!

Get step-by-step solutions from verified subject matter experts

Step: 2 Unlock

Step: 3 Unlock

Document Format (1 attachment)

932-C-O-C (2981).docx

120 KBs Word File

Students Have Also Explored These Related Organic Chemistry Questions!

Tableau and Power BI Project: Data Visualization to Aid Decision - Making Adapted from Hoelscher and Mortimer ( 2 0 1 8 ) ( 2 0 1 8 ) Introduction to data analytics In this case study, you will gain...

Carbon monoxide binds strongly to the Fe2+ ion of the haem group of the protein myoglobin. Estimate the vibrational frequency of CO bound to myoglobin by using the data in Problem 9.2 and by making...

The rate of the reaction between hemoglobin (Hb) and carbon monoxide (CO) was studied at 20oC. The following data were collected, with all concentration units in mmol/ L. (A hemoglobin concentration...

Carbon monoxide is toxic because it binds more strongly to iron in hemoglobin (Hb) than does O2. Consider the following reactions and approximate standard free energy changes:

An alternative method for preparing pure iron from Fe 2 O 3 is by reaction with carbon monoxide. Fe 2 O 3 + CO Fe + CO 2 (Unbalanced) (a) Balance the equation. (Use the lowest possible coefficients.)...

This reaction shows the complete combustion of octane, C 8 H 18 , a component of gasoline. 2 C 8 H 18 ( l ) + 25 O 2 ( g ) 16 CO 2 ( g ) + 18 H 2 O( l ) (a) How many moles of O 2 are needed to burn...

answer '= Completed 14 of 28 Questions Q Unlimited attempts per question. = -5% partial credit for incorrect s Refer to the Biochemistry in Focus section of your text for this chapter to answer this...

Carbon monoxide ( CO ) is toxic to humans because it: a . binds to myoglobin and causes it to denature. b . is rapidly converted to toxic C O 2 . c . binds to the globin portion of hemoglobin and...

1. a) Estimate the Hf of hex-1-yne (assume it is a liquid) using the determined Hcombustion which is -2,816 KJ/mol (assume it is measured at SATP) and the tabled Hf values of CO2(g) and H2O(g). To...

1. The energy involved in chemical reactions A. always appears as light. B. can take many forms. C. always appears as electricity. D. always appears as heat. 2. Sodium sulfite, Na 2SO 3(aq), is added...

Oxygen combines to the protein Hemoglobin with a binding energy of -0.7 eV. Carbon monoxide competes with oxygen for the same binding pocket where it binds with a binding energy of -0.85 eV. Suppose...

Although we shall discuss the naming of organic compounds later when we discuss the individual families in detail, one method of naming alkyl halides is so straightforward that it is worth describing...

How do restrictions affect net assets?

If a C corporation uses straight - line depreciation on real estate ( 5 1 2 5 0 property. no portion of a recogenied gain on the sule of the property will be recipured as ordinary income. True False

SummaryOnline BookwormsA preview of the page you will create is shown below.Instructions ?|Daniel Palmer is a content manager of Online Bookworms, a website dedicated to lovers of books and reading....

Let A = [a;l E Fxn be a square n x n matrix. We define the trace of A to be the number Tr(A) = akk- k=1 a) Prove that Tr : FXn F is a linear function. b) Let A, B e F"X". Prove that Tr(AB) = Tr(BA)....

Mr. Alok ones Mr. Samir Rs. 1650 on 1st Jan 2019 From Jan to March the following further transaction took place between Alok and Samir . January 15 Alok buys goods Rs. 1200 Feb 10- Alok buys goods...

1. To buy a delivery truck, Food-To-Go LLC borrows funds from Grow-Your-Business Inc. secured by the borrowers interest in the truck. The lender files a financing statement but not a continuation...

Timing A Lger Marketing online poll conducted in June of 2013 showed Justin Trudeau of the Liberal party with a four-point lead over current Prime Minister Stephen Harper. Considering the survey...

RECALL Under what conditions are ketone bodies produced?

A friend who is trying to lose weight complains about the odd taste in his mouth in the mornings. He says it seems like a filling has broken loose, and the metallic sensation is bothersome. What...

which of the following queries is used tot determine how many customers belong to the Rochester city from the Customer table

Weasleys Wizard Wheezes produces and sells an assortment of practical joke items, had the following results for May. The budgets for June and July are also given. May (actual_ June (budget) July...

1. Which of the following is not a factor used in determining assessed value? a. Original price b. Improvements c. True cash value d. a, b and c are all factors used 2. Which of the following...