Certain glutamine analogs irreversibly inactivate enzymes that bind glutamine. Identify the nucleotide biosynthetic intermediates that accumulate in

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Certain glutamine analogs irreversibly inactivate enzymes that bind glutamine. Identify the nucleotide biosynthetic intermediates that accumulate in the presence of those compounds.

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Fundamentals of biochemistry Life at the Molecular Level

ISBN: 978-0470547847

4th edition

Authors: Donald Voet, Judith G. Voet, Charlotte W. Pratt

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Question Posted: Apr 30, 2016 02:53 PM

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Certain glutamine analogs irreversibly inactivate enzymes that bind glutamine. Identify the nucleotide biosynthetic intermediates that accumulate in

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PRPP and FGAR accumulate because they are substrates of Reactions 2 and 5 in the IMP biosynthetic pathway Fig 231 XMP also accumulates because the GMP synthetase reaction is blocked Fig 233 Although glutamine is a substrate ...View the full answer

Fundamentals of biochemistry Life at the Molecular Level

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