Draw mechanism arrows to show electron movements in the Bergman cycloaromatization reaction that leads to the diradical believed responsible for the DNA-cleaving action of the antitumor agent calicheamicin (see "Why Do These Topics Matter?" after Section 10.12).

Transcribed Image Text:

HO HO но NHCO2Me NHCO Me NHCO2Me DNA polysaccharide diradical po polysaccharide _ Diradical Diradical O DNA double- stand cleavage