Figure 8.19 shows a proposed mechanism for carboxypeptidase A. In Figure 8.19 a. What is the role
Question:
In Figure 8.19
a. What is the role of Glu 270 in catalysis?
b. What is the role of Arg 145 in catalysis?
Transcribed Image Text:
Bond cleavage NH (R145) 0 Rn (H69) (E72) (H196) (E270) (R145 (H69) (E72) (H196) (E270) (R145 (H69) (E72) (H196) (E270) Release products and bind water
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a E270 acts as a GBC general base catalyst in step one an...View the full answer
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Related Book For
Biochemistry Concepts and Connections
ISBN: 978-0321839923
1st edition
Authors: Dean R. Appling, Spencer J. Anthony Cahill, Christopher K. Mathews
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