BIOL 161 Exam 4

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Biology - Anatomy

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user_pereira_de_andr Created by 9 mon ago

Cards in this deck(100)
individual muscle cell
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group of muscle cells (fibers)
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plasma membrane of skeletal muscle cells
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the cytoplasm of a skeletal muscle cell
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contractile unit of a muscle cell that makes a myofibril (made of thick and thin filaments)
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modified endoplasmic reticulum that regulates calcium in the cell; storage location for calcium
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tubes continuous with the sarcolemma to increase surface area
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major component of muscle cell (takes up the most intracellular volume)
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oxygen-binding protein in a muscle cell
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contains many nuclei
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fibrous connective tissue that is continuous with the tendon
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skeletal and cardiac
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muscle = made of fascicles = made up of muscle fibers (cells) = made up of myofibrils = made up of sarcomere = made up of protein filaments
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protects muscle cells, reduces friction, creates space for extracellular fluid
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epimysium, perimysium, endomysium
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covers entire muscle; outermost layer
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covers fascicles
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covers muscle fibers
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muscle to bone; collagen fibers of epimysium form strong tendons that merge into outer coverings ove bone
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Attaches muscle to bone; made up of dense regular connective tissue
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muscle to bone / indirect
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muscle to muscle; collagen fibers are directly continuous with periosteum; muscle emerges directly from bone
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muscles insert to broad sheet of connective tissue called an aponeurosis
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strong sheet of tissue that acts as a tendon to attach muscles to bone; broad and flat
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circular, convergent, parallel, pennate, fusiform
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fascicles concentrically arranged around an opening - ex. mouth
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fascicles from a broad area converge on a common attachment - ex. pectoralis major
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fascicles parallel to long axis of muscle; sartorius
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fascicles attach at an angle to a central tendon
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excitability, conductivity, contractility, elasticity
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ability to respond to stimuli; responds to chemicals released from motor neurons
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ability to propagate electrical signals over membrane; conduct charge
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ability to be stretched without damaging the tissue
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ability to return to original shape after being stretched
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skeletal
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smooth, cardiac
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smooth
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skeletal
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cardiac, smooth
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attached to bone or fascia; looks like lines; distinct dark and light regions; long/cylindrical
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autorhythmic (self-regulate); branched
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blood vessels; line walls of hollow organs
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myosin
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can bind and hydrolyze ATP
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actin, troponin, tropomyosin
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has an active site that can bind to the head of a myosin protein
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binds and regulates tropomyosin; in the presence of calcium it moves tropomyosin off of active sites; BINDS TO CALCIUM
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covers active actin sites when muscles are relaxed
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only thin filaments
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only thick filaments
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boundary between sarcomeres
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midline of sarcomere
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contains M line
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stores oxygen for use
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thin filaments move toward the center of the sarcomere causing sarcomeres to move closer together and cause muscle contraction
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sarcomere shortens, H zone disappears, I band shortens, A band stays same size
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actin, elastin
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they do not move
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synapse between a motor neuron and a muscle cell
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sarcolemma region associated with the neuromuscular junction; contains chemically-gated ion channels
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neurotransmitter released into the neuromuscular junction
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excitation, excitation-contraction coupling, contraction, relaxation
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communication between neuron and muscle cell leads to an action potential
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conversion of action potential in muscle cell to activation of proteins in the sarcomere
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sliding filament theory
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return of muscle cells to resting length
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bind to acetylcholine the the post-synaptic membrane
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motor end plate
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breaks down acetylcholine in the synaptic cleft
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cation chemical gated channels (K or Na)
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Release of cross-bridge (interaction) between actin and myosin; Movement of calcium ions back into the sarcoplasmic reticulum after contraction ends; Conformation change of myosin from the bent conformation to the extended (activated) conformation.
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sarcolemma
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Cross-bridges would form in the absence of an action potential from a motor neuron.
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active transport protein found in SR
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sarcolemma
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diffuses out of SR into the sarcoplasm
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actin and myosin
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Release myosin from actin active sites; To cause myosin to change shape to the cocked (extended) position.
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less
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At rest, the H-band is about half the length of the A-band
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A
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depolarizes / excites sarcolemma
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1. action potential from motor neuron 2. secretion of ach hormone into synaptic cleft (creates end plate potential) 3. end plate potential triggers an action potential sarcolemma
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ca voltage gated channel allows ca to enter cell and secrete into the synaptic cleft
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chemically gated ach receptors lead to depolarization of end plate potential voltage gated cation channels propagate action potentials
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translate depolarization of sarcolemma into changes of proteins
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1. action potential travels down T-tubule 2. Ca voltage gated channels connected to mechanically gated Ca channels open 3. Ca diffuses into sarcoplasm 4. actin's binding sites revealed
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ca voltage gated channels open
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ca mechanically gated channels open and diffusion of Ca into sarcoplasm
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troponin binds to ca tropomyosin - changes shape / moves off of the myosin binding site on actin actin - ready to bind to myosin
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shorten the sarcomere so the muscle can shorten; cross-bridge cycle
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1. myosin hydrolyzes ATP into ADP and P; myosin extends 2. myosin binds to actin = cross bridge formation 3. ADP + P released and myosin head flexes; thin filament pulled towards m-line; sarcomere shortens (sliding filament theory) 4. ATP binds to myosin and cross bridge breaks
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stop contraction, return sarcomere to resting length
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1. action potentials from somatic motor neuron stop 2. secretion of ach stops; ach broken down by ache; no more muscle exciton = no more end plate potential 3. ca pumped back into SR - cross bridge can no longer form; tropomyosin covers binding site again
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ache breaks down ach
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ca pumps use ATP to pump ca back into the SR
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