Fusidic acid is a steroid like microbial product that is an extremely potent antibiotic with a broad

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Fusidic acid is a steroid like microbial product that is an extremely potent antibiotic with a broad spectrum of biological activity. Its molecular shape is most unusual and has supplied important clues to researchers investigating the methods by which steroids are synthesized in nature.
Fusidic acid is a steroid like microbial product that is

(a) Locate all the rings in fusidic acid and describe their conformations.
(b) Identify all ring fusions in the molecule as having either cis or trans geometry.
(c) Identity all groups attached to the rings as being either α- or β-substituents.
(d) Describe in detail how this molecule differs from the typical steroid in structure and stereo-chemistry. (As an aid to answering these questions, the carbon atoms of the framework of the molecule have been numbered.)

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Organic Chemistry structure and function

ISBN: 978-1429204941

6th edition

Authors: K. Peter C. Vollhardt, Neil E. Schore

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