Question: Hydrogen bonding of substrates to enzymes often involves the polypeptide backbone rather than amino acid side chains. What backbone-substrate hydrogen bond helps distort NAM in

Hydrogen bonding of substrates to enzymes often involves the polypeptide backbone rather than amino acid side chains. What backbone-substrate hydrogen bond helps distort NAM in the D subsite of lysozyme? Can this hydrogen bond form when N-acetylxylosamine is in the active site?

0. 011 H H NHCOCH3 N-Acetylxylosamine

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