In a study of the Gender Aide method of gender selection, 1000 users of the method gave

Question:

In a study of the Gender Aide method of gender selection, 1000 users of the method gave birth to 540 boys and 460 girls. There is about a 1% chance that such extreme results would occur if the method had no effect.
Determine whether the results appear to have statistical significance, and also determine whether the results have practical significance.