Isabella, a 6-year-old child who has been raised in a germ-free environment from birth, is a victim

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Isabella, a 6-year-old child who has been raised in a germ-free environment from birth, is a victim of one of the most severe examples of an abnormal immune system. Isabella also suffers from cancer caused by the Epstein-Barr virus. Relative to this case:
(a) What is the usual fate of children with Isabella's condition and similar circumstances if no treatment is attempted?
(b) Why is Isabella's brother chosen as the hematopoietic stem cell donor?
(c) Why is her physician planning to use umbilical cord blood as a source of stem cells for transplant if her brother's stem cells fail (what are the hoped-for results)?
(d) Attempt to explain Isabella's cancer.
(e) What similarities and dissimilarities exist between Isabella's illness and AIDS?
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Human Anatomy and Physiology

ISBN: 978-0321927040

10th edition

Authors: Elaine N. Marieb, Katja Hoehn

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