Question: Let's suppose a cell line has become malignant because it has accumulated mutations that inactivate two different tumor-suppressor genes. A researcher followed the protocol described

Let's suppose a cell line has become malignant because it has accumulated mutations that inactivate two different tumor-suppressor genes. A researcher followed the protocol described in the experiment of Figure 24.12 and isolated DNA from this mutant cell line. The DNA was used to transform normal fibroblast (NIH3T3) cells. What results would you expect? Would you expect a high number of malignant foci or not? Explain your answer.

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