One type of insoluble support used for SPPS is polymer-bound 4-benzyloxybenzyl alcohol, also known as Wang resin,

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One type of insoluble support used for SPPS is polymer-bound 4-benzyloxybenzyl alcohol, also known as "Wang resin," shown in Fig. 24.8. The 4-benzyloxybenzyl alcohol moiety serves as a linker between the resin backbone and the peptide. After purification, the completed polypeptide can be detached from the resin using trifluoroacetic acid under conditions that are mild enough not to affect the amide linkages. What structural features of the linker make this possible?
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Organic Chemistry

ISBN: 978-1118133576

11th edition

Authors: Graham Solomons, Craig Fryhle, Scott Snyder

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