An article in the Journal of Applied Physiology [Humidity Does Not Affect Central Nervous System Oxygen Toxicity

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An article in the Journal of Applied Physiology [€œHumidity Does Not Affect Central Nervous System Oxygen Toxicity€ (2001, Vol. 91, pp. 1327€“1333)] reported that central nervous system (CNS) oxygen toxicity can appear in humans on exposure to oxygen pressures >180 kPa. CNS oxygen toxicity can occur as convulsions (similar to epileptic seizures, grand mal) and loss of consciousness without any warning symptoms. CNS oxygen toxicity is a risk encountered in several fields of human activity, such as combat diving with closed-circuit breathing apparatus and diving with mixtures of nitrogen and oxygen (nitrox) or nitrogen, oxygen, and helium (trimix) in sport and professional diving to epths >30 μ. The risk of oxygen toxicity is always considered when deep diving is planned. The following data demonstrate shortened latencies in a dry atmosphere (<10% humidity) in 11 rats at O2of 507 kPa. The data collected are as follows:

22 37 18 27 19 26 19 27 18 23 14

(a) Given the following probability plot of the data, what is a logical assumption about the underlying distribution of the data?

(b) Explain why this check of the distribution underlying the sample data is important if you want to construct a confidence interval on the mean.

99 95 90 80 70 60 * 50 40 30 20 10 10 20 30 Latency Percent

(c) Find the 95% confidence interval for the mean.

(d) Explain why this check of the distribution underlying the sample data is important if you want to construct a confidence interval on the variance.

(e) Find the 95% confidence interval for the variance.

Distribution
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Applied Statistics And Probability For Engineers

ISBN: 9781118539712

6th Edition

Authors: Douglas C. Montgomery, George C. Runger

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