Question: Questions: 1. Determine the normal prior for ar based on the data from (a) the GISSI-2 study, (b) the ISIS-3 study, and (c) the combined

Questions: 1. Determine the normal prior for ar based on the data from

(a) the GISSI-2 study,

(b) the ISIS-3 study, and

(c) the combined data from the GISSI-2 and ISIS-3 studies. Table 3.1 Data from GUSTO-1, GISSI-2 and ISIS-3 on the comparison between of streptokinase and rt-PA. Trial Drug Number of patients Number of deaths Number of nonfatal strokes Combined deaths or strokes GUSTO SK 20173 1473 101 1574 rt-PA 10343 652 62 714 GISSI-2 SK 10396 929 56 985 rt-PA 10372 993 74 1067 ISIS-3 SK 13780 1455 75 1530 rt-PA 13746 1418 95 1513

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