Predict the effect of each of the following mutants on the rate of glycolysis in liver cells
Question:
Predict the effect of each of the following mutants on the rate of glycolysis in liver cells (increase, decrease, no change):
(a) Loss of the allosteric site for ATP in PFK-1
(b) Loss of the binding site for citrate in PFK-1
(c) Loss of the phosphatase domain of PFK-2/FBPase-2
(d) Loss of the binding site for fructose-1,6-bisphosphate in pyruvate kinase
(e) Loss of acetyl-CoA binding site in pyruvate carboxylase
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Lets predict the effect of each of the mentioned mutants on the rate of glycolysis in liver cells a Loss of the allosteric site for ATP in PFK1 Phosph...View the full answer
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Related Book For 
Biochemistry Concepts And Connections
ISBN: 9780134641621
2nd Edition
Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews
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