Propose a mechanism for the TPP-dependent step in isoleucine biosynthesis (see Figure 18.20). Draw the predicted product

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Propose a mechanism for the TPP-dependent step in isoleucine biosynthesis (see Figure 18.20). Draw the predicted product of this reaction.

Figure 18.20.

Isoleucine Threonine Serine-threonine PLP dehydratase NH3 CH3 -CH-C-coo a-Ketobutyrate OH Isoleuclne

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Biochemistry Concepts And Connections

ISBN: 9780134641621

2nd Edition

Authors: Dean Appling, Spencer Anthony-Cahill, Christopher Mathews

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