Question: Use the appropriate sample size formula to work out how many patients in each group need to be recruited to such a trial with a

Use the appropriate sample size formula to work out how many patients in each group need to be recruited to such a trial with a 5% (two‐sided) significance level and a power of 90%?

A. 291 B. 389 C. 582 D. 778 E. 1251

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