Three different medicine manufacturers test the effectivess of their own brand of medicine for curing patients of a certain illness.

The results of the tests are as follows:

• Manufacturer A tested 1 patient and the patient recovered. They claim that their medicine is effective in 100% of cases.

• Manufacturer B tested 100 patients and 60 recovered. They claim that their medicine is effective in 60% of cases.

• Manufacturer C tested 10 000 patients and 5000 recovered. They claim that their medicine is effective in 50% of cases.

Which manufacturer’s claim is the most reliable? Justify your answer.