Treating a particular polypeptide with one reagent (as described in the previous problem) produced the fragments: Treating

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Treating a particular polypeptide with one reagent (as described in the previous problem) produced the fragments:Gly-Glu-Ser-Lys Trp-Arg Leu-Thr-Ala-Trp

Treating the same polypeptide with a different reagent produced the fragments:Gly-Glu Thr-Ala-Trp Ser-Lys-Trp-Arg-Leu

What is the amino acid sequence of the polypeptide?


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Determining the amino acid sequence in a protein usually involves treating the protein with various reagents that break up the protein into smaller fragments that can be individually sequenced. Treating a particular 11-amino acid polypeptide with one reagent produced the fragments:Ala-Leu-Phe-Gly-Asn-Lys Trp-Glu-Cys Gly-Arg

Treating the same polypeptide with a different reagent produced the fragments:Glu-Cys Gly-Asn-Lys-Trp Gly-Arg-Ala-Leu-Phe

What is the amino acid sequence of the polypeptide?

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