Question: 6. Consider the following McNemars table from the study analyzed by Donovan et al. (1984). This is a pair-matched case-control study, where the cases are

6. Consider the following McNemar’s table from the study analyzed by Donovan et al. (1984). This is a pair-matched case-control study, where the cases are babies born with genetic anomalies and controls are babies born without such anomalies. The matching variables are hospital, time period of birth, mother’s age, and health insurance status. The exposure factor is status of father (Vietnam veteran ¼ 1 or nonveteran ¼ 0): Case E not E Control E 2 121 not E 125 8254 For the above data, carry out McNemar’s test for the significance of exposure and compute the estimated odds ratio. What are your conclusions?

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