Question: 10.102 Adverse side effects are always a concern when testing and trying new medicines. Placebocontrolled clinical studies were conducted in patients 12 years of age

10.102 Adverse side effects are always a concern when testing and trying new medicines. Placebocontrolled clinical studies were conducted in patients 12 years of age and older who were receiving

“once-a-day” doses of Allegra, a seasonal allergy drug. The following results were published in the April 2005 edition of Readers’ Digest.

Allegra (dose once a day) Placebo (dose once a day)

Side effects n 283 n 293 Number reporting headaches 30 22 Determine, at the 0.05 level of significance, whether there is a difference in the proportion of patients reporting headaches between the two groups.

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