The curve shown in Figure 435 is described by the MichaelisMenten equation: rate (v) = Vmax [S]/(KM

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The curve shown in Figure 4−35 is described by the Michaelis–Menten equation:

rate (v) = Vmax [S]/(KM + [S])

Can you convince yourself that the features qualitatively described in the text are accurately represented by this equation? In particular, how can the equation be simplified when the substrate concentration [S] is in one of the following ranges: (A) [S] is much smaller than the KM, (B) [S] equals the KM, and (C) [S] is much larger than the KM?

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Essential Cell Biology

ISBN: 9780393680362

5th Edition

Authors: Bruce Alberts, Karen Hopkin, Alexander Johnson, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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