Question: 16.26 The placebo effect. The placebo effect is particularly strong in patients with Parkinson's disease. To understand the workings of the placebo effect, measure activity

16.26 The placebo effect. The placebo effect is particularly strong in patients with Parkinson's disease. To understand the workings of the placebo effect, measure activity at a key point in the brain when patients receive a placebo that they think is an active drug and also when no treatment is given. The same six patients were measured both with and without the placebo, at different times.

(a) Explain why the proper procedure to compare the mean response to placebo with control (no treatment) is a matched pairs t test.

(b) The six differences (treatment minus control) bad x = —0.326 and s 0.181. Is there significant evidence of a dif ference between treatment and control?

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