Draw the structure of the double Holliday junction that would result from strand invasion by both ends

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Draw the structure of the double Holliday junction that would result from strand invasion by both ends of the broken duplex into the intact homologous duplex shown in Figure Q5–3. Label the left end of each strand in the Holliday junction 5ʹ or 3ʹ so that the relationship to the parental and recombinant duplexes is clear. Indicate how DNA synthesis would be used to fill in any single-strand gaps in your double Holliday junction.


Figure Q5-3

5' 3' 5' 3'

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Molecular Biology Of The Cell

ISBN: 9780815344322

6th Edition

Authors: Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

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