lnositoll,4,5-trisphosphate (IP1) and diacylglycerol (DAG) are second messenger molecules derived from the cleavage of the phosphatidylinositol 4,5-bisphosphate
Question:
lnositoll,4,5-trisphosphate (IP1) and diacylglycerol (DAG) are second messenger molecules derived from the cleavage of the phosphatidylinositol 4,5-bisphosphate (PlP2) by activated phospholipase C. Describe the role of IP3 in causing a rise in cytosolic Ca2+ concentration. How do cells restore resting levels of cytosolic Cal2+? What is the principal function of DAG?
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Cleavage of PIP 2 by phospholipase C generates IP 3 and DAG IP ...View the full answer
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Related Book For 
Molecular Cell Biology
ISBN: 978-1429234139
7th edition
Authors: Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Anthony Bretscher, Hidde Ploegh, Angelika Amon, Matthew P. Scott
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