Show how you would modify the synthesis given in the previous problem to synthesize the following drugs:
Question:
Show how you would modify the synthesis given in the previous problem to synthesize the following drugs:
(a) Bromodiphenhydramine (an antihistamine), where R1 = Br, R2 = H
(b) Orphenadrine (an antispasmodic, used in controlling Parkinson’s disease), where R1 = H, R2 = CH3
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a The nitrogen of the bromide 1 will be replaced by a methyl group and t...View the full answer
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Related Book For 
Organic Chemistry
ISBN: 978-1118875766
12th Edition
Authors: T. W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder
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