A histidine residue (B), one of the functional groups in the structure of a certain enzyme, has
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A histidine residue (B), one of the functional groups in the structure of a certain enzyme, has a conjugate-acid pKa = 7.8. What is the fraction of each form (BH and B) present at physiological pH (pH = 7.4)?
Transcribed Image Text:
(enzyme) :N CH₂ H B N: + H₂0 (enzyme) CH₂ :N- H + NH BH (pK₂ = 7.8) + H₂O
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